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العنوان
The relation between plasma concentration of osteopontin and matrix metalloproteinase-2 and severity of chronic heart failure /
الناشر
Alaa Abdalhamid Mohammed Ali ,
المؤلف
Alaa Abdalhamid Mohammed Ali
هيئة الاعداد
باحث / AlaaAbd Al- Hamid Mohammed Ali
مشرف / Amina Kamal El-Dein El-ansary
مشرف / Yaser Ahmed Abd El-Hady
مشرف / Salwa Fayez Hasan
مشرف / Ghada Mahmoud Abd El-Aziz
تاريخ النشر
2012
عدد الصفحات
155 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة القاهرة - كلية الطب - Medical Biochemistry
الفهرس
Only 14 pages are availabe for public view

from 183

from 183

Abstract

Extracellular matrix remodeling is thought to play an important role in the progression of heart failure (HF). Matrix metalloproteinases-2 (MMPs) havebeen demonstrated to influence left ventricular properties and serve as targets of potential anti-remodeling agents. osteopontin, a glycoprotein that can be detected in plasma, was found to be up regulated in several animal models of cardiac failure and may thus represent a new biomarker that facilitates risk stratification in patients with heart failure