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العنوان
Enamines as intermediates in the heterocyclic synthesis /
المؤلف
Mohamed, Abd Elgaber Tarhoni Rezk.
هيئة الاعداد
باحث / عبدالجابر طرهونى رزق محمد
مشرف / أحمد على حامد فضة
مشرف / المتولى حموده المتولى
مشرف / سمير بھجت عبد الرازق بندق
الموضوع
Heterocyclic compounds Synthesis. Enamines.
تاريخ النشر
2011.
عدد الصفحات
296 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الكيمياء
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة المنصورة - كلية العلوم - الكيمياء
الفهرس
Only 14 pages are availabe for public view

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Abstract

The aim of this thesis is to synthesize some novel heterocyclic compounds starting from easily obtainable enamines. Therefore, the work have been divided into two parts; the first one is the synthesis of acyclic enamine, namely 2-cyano-3-(dimethylamino)-N-(4-phenylthiazol-2-yl)acylamide and study its behavior towards some different nucleophiles. The second part is the synthesis of aminopyrazole derivative which has a latent enamine skeleton and study its reactivity towards various types of 1,3-biselectophilic reagents. Part 1: In this part we employed enaminonitrile derivative to synthesize some new polyfunctionally heterocyclic compounds such as isoxazole, aminopyrazole, pyrimidine, diazepine, pyran, pyridine and coumarin derivatives. spectral data. Part 2: In this part we employed 5-aminopyrazole derivative to synthesize some new polyfunctionally heterocyclic compounds such as, pyrimidine, imidazole, triazine and thiadiazine derivatives.