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العنوان
Metabolic syndrome in childhood cancer survivors /
المؤلف
Abo El-Hassan, Hossam El-Din Samir.
هيئة الاعداد
باحث / حسام الدين سمير أبوالحسن
مشرف / أحمد كمال منصور
مشرف / مصطفي عبدالعال حجازي
مناقش / عبدالرحمن محمد المشد
مشرف / سمه أسامه شومان
الموضوع
Cancer-- Patients. Metabolic syndrome.
تاريخ النشر
2011.
عدد الصفحات
103 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة المنصورة - كلية الطب - طب الاطفال
الفهرس
Only 14 pages are availabe for public view

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Abstract

The metabolic syndrome is a cluster of multiple clinical and laboratory parameters including obesity, dyslipidemia, hypertension and insulin resistance with hyperglycemia . Several definitions has been proposed form metabolic syndrome by WHO, Unicef, ATPIII and IDF. Childhood metabolic syndrome needs particular consideration when interpreted its parameters in children and adolescence. Thus the new IDF definition is divided according to age-groups because of developmental challenges (as mentioned before) presented by age-related differences in chil¬dren and adolescents: age 6 years to younger than 10 years; age 10 years to younger than 16 years; and 16 years or older. Children who are younger than 6 years were excluded from the definition because of insuf¬ficient data for this age-group. In all three age groups, abdominal obesity is the “sine qua non”. The primary purpose of identifying the MetS is to identify a clustering of features that were associated with increased CVD risk. As the term syndrome implies, a specific causative etiology to the MetS is not clear. Nevertheless, abdominal adiposity and insulin resistance appear to be at the core of the pathophysiology of the MetS and its individual components .Abdominal obesity is the driving force in the prevalence of insulin resistance.