الفهرس 
Introduction and aim of workOnly 14 pages are availabe for public view
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Abstract
Colorectal cancer (CRC) is the second most common cause of cancer-related death in the United States. Improved adherence to CRC screening guidelines and the subsequent prevention of polyp progression to cancer has led to a recent decline in the incidence and mortality from CRC. Approximately one-third of patients with CRC have their cancer limited to the rectum. It is often regarded as a disease of the elderly with a peak incidence in the 6th and 7th decades. Recently several studies from different countries have reported colorectal carcinoma occurring in patients below 40 years of age. Colorectal carcinoma in patients under 40 years of age is unusual, and delay in diagnosis is common. The distribution of lesions is more homogeneous than that seen in older patients, and high- grade malignancies are more frequent. It has been suggested that low survival in this young age group is due tumor aggressive histological grades of tumors, low suspicion of malignancy in young people and delay in diagnosis. In Egypt, colorectal cancer is the seventh most common cancer and more than half of the patients are under the age of 50. The CRC is the most common malignancy of gastrointestinal tract. Although CRC is often thought of as a disease of the elderly, the results of the current study demonstrate an increase in the incidence of rectal and rectosigmoid cancer in young patients. This rise was observed independent of sex or race. Risk factors for this include a genetic predisposition to colon cancer or diet and lifestyle changes in the current era leading to a rise in the incidence of cancers in young patients.