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العنوان
Clinical and immunological studies in bronchopneumonia in calves with special reference to pro-inflammatory mediators /
المؤلف
Hassan, Mohamed Abdo Mohamed.
هيئة الاعداد
باحث / Mohamed Abdo Mohamed Hassan
مشرف / Mohamed A. A. Youssef
مشرف / Sabry A. El-Khodary
باحث / Mohamed Abdo Mohamed Hassan
الموضوع
Bronchopneumonia.
تاريخ النشر
2011.
عدد الصفحات
133 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة المنصورة - كلية الطب - Department of Internal Medicine, Infectious and Fish Diseases
الفهرس
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Abstract

Bronchopneumonia continues to be a major problem for the bovine and buffalo calves and constitute a source of economic loss. Bronchopneumonia affects the diseased animal immunity. To evaluate the immune status during bronchopneumonia, venous blood samples were obtained from (89) bovine and buffalo calves (51 bovine and 38 buffalo), on which, (69) bovine and buffalo calves (38 bovine & 31 buffalo) exhibited clinical signs of bronchopneumonia. Moreover, (20) apparently healthy calves (13 bovine and 7 buffalo) were selected and served as control group. (24) Bovine calves and (24) buffalo calves exhibiting clinical signs of acute bronchopneumonia were selected to receive treatment. All of the treated groups were received antibiotic therapy represented by florfenichol and devided according to the anti-inflammatory medicaments into three groups; the first group received diclofenac sodium, the second group received flunixine meglumine, while the third one received dexamethasone. Venous blood samples were collected at three occasions; before treatment and at 6 and 12 days posttreatment. The fibrinogen and haptoglobin levels revealed a significant increase in diseased calves in comparison with those of the control group as well as those with chronic cases. In contrast, the immunoglobulin A, immunoglobulin G levels and albumin showed a significant decrease in diseased calves in comparison with those of the control group and in those with acute bronchopneumonia in comparison with chronic cases. In this investigation, it could be concluded that the Hp and IgG levels were higher in pneumonic buffalo calves than in bovine ones. Regarding the treatment outcomes, all the selected parameters returned to the normal reference limits one and two weeks posttreatment but the treatment with flunixine meglumine showed the highest efficacy.