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العنوان
Design, synthesis and antitumor activity of some new 1,3,4-oxadiazole derivatives and their nucleosides /
المؤلف
Zidan, Tayseer Abd El - Hameed Abd El - Dayem.
هيئة الاعداد
باحث / Tayseer Abd El-Hameed Abd El-Dayem Zidan
مشرف / Ahmed Ali Fadda
مشرف / Adel Abd El-Hady Nassar
مشرف / Wael Abd El-Hafeez Shendy
الموضوع
Antioxidants in health and disease.
تاريخ النشر
2011.
عدد الصفحات
228,10,I-IX p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكيمياء
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة المنصورة - كلية العلوم - Chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

A number of some new 1,3,4-oxadiazole derivatives were synthesized. The structures of all of the synthesized compounds were confirmed by their spectral and analytical data; IR, 1H NMR and mass spectra which all agreed with the assigned structures. The prepared compounds were tested for their antioxidant, cytotoxicity, and antitumor activity. They displayed significant antioxidant and anticancer activities against HepG2 (human hepatocellular liver carcinoma cell line), WI 38 (skin carcinoma cell lines), VERO (cell line was initiated from the kidney of a normal adult African green monkey), MCF-7 (breast cancer cell lines).