الفهرس 
immunodeficienciesOnly 14 pages are availabe for public view
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Abstract
The term ‘primary’ is taken to mean that the immunodeficiency is not secondary to any known infection, lymphoreticular malignancy, or drugs. Primary immunodeficiencies (PIDs) are still underestimated, that there remains a significant delay in their diagnosis. Technology and organizational structures available to measure the true incidence/prevalence statistics are improving. Primary T-cell & B-cell immunodeficiencies can be classified into: • Cellular (T-cell) immunodeficiencies (as DiGeorge syndrome, chronic mucocutaneous candidiasis) • Antibody (B-cell) immunodeficiencies (as X-linked agammaglobulinemia, Transient hypogammaglobulinemia of infancy, Common variable immunodeficiency) • Combined T-cell (cellular) and B-cell (antibody) deficiencies (as severe combined immunodeficiency, combined immunodeficiency with T-cell membrane or signaling defects, wiskott aldrich syndrome) • Other PIDs (as forkhead box N1 deficiency, immune dysregulation–polyendocrinopathy–enteropathy –X-linked syndrome) The Laboratory serves as the primary source of diagnostic information used to define the immunologic defect. The lines of treatment are antimicrobial therapy, Thymus transplantation, Ig replacement, Haematopoietic stem cell transplantation.