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Abstract The aim of the work: Review of literature in a comparative study between crosslinking and Intacs as safe and effective treatment of keratoconus (Greek: kerato – horn, cornea; and kono – cone) is a degenerative, non-inflammatory corneal disorder, characterised by central and para-central stromal thinning and conical ectasia. The management of keratoconus depends on the degree of ectasia. Early cases can be corrected effectively with astigmatic spectacle correction and soft toric contact lenses. Intrastromal corneal ring segments (ICRS) are small semicircular plastic segments that are inserted, usually under topical anaesthesia, into stromal channels outside the central visual axis of the eye to reinforce the corneal stroma. The DROPs are then activated by a special UV light. The method works by increasing collagen cross-linking, which are the natural “anchors” within the cornea. These “anchors” are responsible for preventing the cornea from bulging out and leading to a decrease in vision. Conclusion: The method of cross linking using riboflavin and UVA is technically simple and less invasive than all other therapies proposed for keratoconus. Unlike other mini-invasive methods, such as intrastromal rings (INTACS) and excimer laser surgery , which do not block keratectasia but mainly treat the refractive effects of the disease, this method can treat and prevent some of the underlying pathophysiologic mechanisms. |