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Abstract
The episode Alberasul cornerstone of many compounds that have a lot of biological significance, especially NSAIDs non ستيرويديه and which is characterized as having Tatherfal and the degree of low toxicity., And therefore have been in this letter a study of reference for the importance of biological and preparation methods different, as well as chemical properties of loop Alberasul., and the purpose of the preparation of many derivatives Alberasul and the related the other بيرازول rings or Birol or Ooxadyasul of the, Thiadyasul or Trellazul, as well as fused rings of different Berasulutrellazen because of reported importance of high Oqrbazinah both the aforementioned episodes. And has been preparing a number Forty-four new compounds have been identified on the exact chemical composition analysis of the basic elements, as well as infrared and magnetic resonance of the hydrogen atom and sometimes mass spectrometer. It has been shown after conduct Aloqrbaziny survey of eight new vehicles that some of which are highly effective as anti-inflammatory comparing drug diclofenac sodium is known so far, which is used dynamically as an anti-inflammatory rheumatic. For example, compounds containing derivatives sulfadiazine and الأنتيبيرين were were most effective, while vehicles that have derivatives Alberazulun and Alberasul and some Alheidrazonat the found to be less effective. Has been the preparation of new compounds through five plans research, which included the preparation of a compound ethyl 5 - (4 - chlorophenyl) - ((II and hydrazine III derived from using hydrazine and solvents multiple different temperatures. Notably, hydrazine, which contains on Alberasul ring has been prepared in more ways than one is considered basic compound for the preparation of the rest of the compounds of this message.