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Abstract Maintenance of body core temperature within narrow limits is a major homeostatic function critical for survival. Thermal sensation (cold or heat sensation) is opposed through two sets of receptors which are central and peripheral thermosensors; the peripheral thermosensors are either shell receptors located in the skin to receive environmental temperature and core receptors locater in visceral organs to receive the core temperature. Core temperature may fluctuate slightly but is maintained within a relatively narrow zone (within 0.2 to 0.5 °C) by adjustments of skin vasomotor responses; only larger fluctuations of core temperature above or below certain threshold zones activate sweating or shivering responses. Hypothermia as a disease may be primary (accidental, environmental) or secondary due to underlying defect in thermoregulatory pathways, accidental hypothermia is primarily a disease of elderly in cold weathered countries with a high death rate and well published strategies to prevent such a risk. |