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العنوان
Thoracic complications in liver transplant recipients /
الناشر
Dina Abo El-Khair Abd-Allah,
المؤلف
Abd-Allah, Dina Abo El-Khair.
هيئة الاعداد
باحث / دينا أبو الخير عبد الله
مشرف / محمد السيد الدسوقى
مشرف / مجدى محمود عماره
مشرف / مأمون محمد عاشور
مناقش / أمينة محمود عبد المقصود
الموضوع
Liver Transplantation-- Complications-- Diagnosis.
تاريخ النشر
2008.
عدد الصفحات
200 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
1/1/2008
مكان الإجازة
جامعة المنصورة - كلية الطب - الأمراض الصدرية
الفهرس
Only 14 pages are availabe for public view

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Abstract

Liver transplantation is the definitive treatment for patients with acute ‎liver failure, end-stage liver disease, and in primary hepatic ‎malignancies. For patients with successful liver transplantation, the ‎probability of long-term graft and recipient survival is generally excellent, ‎with a high likelihood of return to a relatively normal lifestyle. However, ‎liver transplantation is associated with a number of potentially fatal ‎complications.‎ Thoracic complications are classified into infectious and non-infectious. ‎As regard infectious thoracic complications, the lungs are particularly ‎vulnerable, representing the second most common site of infection in ‎liver transplant recipients after intra-abdominal infection. The risk of ‎infection is determined by the intensity of exposure to infectious agents ‎and the overall immunosuppression level Noninfectious thoracic complications in liver transplant recipients include ‎atelectasis, right-sided diaphragmatic dysfunction, pleural effusions, ‎pulmonary edema, prolonged ventilatory support for more than 24 hours, ‎and pulmonary thromboembolism. Moreover, pulmonary metastatic ‎calcification has also been described in liver transplant recipients. In ‎addition, hepatopulmonary syndrome and portopulmonary hypertension ‎represent two unusual pulmonary complications of advanced liver ‎disease. Although their onset precedes liver transplantation, these ‎disorders do not immediately correct after this intervention and they can ‎therefore contribute significantly to posttransplantation morbidity and ‎mortality. The use of immunosuppressive therapy is also associated with ‎certain pulmonary complications as alveolar hemorrhage, interstitial ‎pneumonitis, posttransplant lymphoproliferative disorders, and ‎bronchogenic carcinoma.‎