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العنوان
Role of helicabacter pylori as acause of gastritis in children /
المؤلف
El-Hadad, Mostafa Ahmed.
هيئة الاعداد
باحث / مصطفي أحمد الحداد
مشرف / أحمد كمال منصور
مشرف / أسامة سعد سلامة
مشرف / محمد عز الرجال عباس
الموضوع
Helicobacter Pylori.
تاريخ النشر
2005 .
عدد الصفحات
195 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2005
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم طب الأطفال
الفهرس
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Abstract

The proposed study was conducted to determine the role of H.pylori as a cause of gastritis in children and to establish its endoscopic and pathologic characters. As can be seen from the results of this study it was concluded that H. pylori is a major cause of gastritis among children as it was responsible for about one third of the studied cases. Concerning the clinical manifestations associated with H. pylori gastritis, RAP is the commonest since it was found in more than half of the studied cases followed by H&M and ulcer like dyspepsia in the form of persistent vomiting and nausea. However other manifestations were recorded (fatigue, malaise and diarrhea). Incidence of H.pylori infection increases with increasing age as shown from the mean age 9.06 years, at the same time there is no significant difference between male and female as regards the infection. Regarding the endoscopic finding of upper GIT endoscopy associated with H.pylori gastritis, it is concluded that antral nodularity is the most reliable feature of its diagnosis whereas free endoscopy which was presented in about half of cases did not exclude infection with H.pylori. Upper GIT endoscopy remains the gold standard for diagnosis of H.pylori infection pushing researches to make better of non invasive methods. In relation to the esophageal endoscopic finding associated with H.pylori gastritis, most of cases were free in spite of esophagitis and varices which were reported in minor cases. At the same time endoscopy of the duodenum was free in most of them while duodenitis, duodonopathy and nodularity were recorded. As regards the pathological examination of gastric body and antral biopsies, diffuse gastritis with pure antral predominance was reported in almost all the cases whereas locally affected cases were very rare. The majority of cases were of moderate degree while mild and severe were so rare. Associated duodenal biopsies reviled that about half of them were free whereas the other half were associated with non specific duodenitis, the majority of them were mild. In spite of presence of significant association between the clinical manifestation and endoscopic finding of the stomach, there was no association between the clinical manifestation and pathological finding of it.