الفهرس 
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Abstract
In the present investigation, new series of arylsulfonylurea derivatives containing imidazolidinedione, pyrimidinetrione and quinazolinedione nuclei were prepared. The structures of these compounds were determined by elemental microanalysis, 1H-NMR, IR and mass spectroscopy. All the newly synthesized final compounds were subjected to in vitro DNA-binding screening, while three of these compounds were tested in vivo against Ehrlich Ascites Carcinoma in mice. The results showed that two of the three tested compounds exhibited potent antitumor activity.