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العنوان
Immunochemical Evaluation of Tumor Necrosis Factor In HCV Infection Using Monoclonal Antibody /
المؤلف
Hegazy, Ola Hegazy Mohamed.
هيئة الاعداد
باحث / علا حجازى محمد حجازى
مشرف / احمد محمود عابدين
مشرف / عبدالفتاح محمد عطاالله،
مشرف / ابراهيم الدسوقى محمد
مشرف / احمد محمود عابدين
الموضوع
Tumor necrosis factor. Liver Diseases - Therapy.
تاريخ النشر
2006.
عدد الصفحات
150 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الحيوان والطب البيطري
تاريخ الإجازة
1/1/2006
مكان الإجازة
جامعة المنصورة - كلية العلوم - Department of Zoology
الفهرس
Only 14 pages are availabe for public view

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Abstract

In the present study, Serum samples of 40 HCV­infected patients positive for total anti­HCV antibodies, and they were 30 males (75%) and 10 females (25%). In addition, serum samples from 8 healthy individuals were used as negative controls. The following results were detected using ELISA techniques:­ (60%) out of serum samples were positive for anti­HCV IgG, and (40%) were negative. (77.5%) out of serum samples were positive for anti­HCV IgM; While, (22.5%) were negative. (65%) out of serum samples were positive for HCV antigen. While, (35%) were negative.In conclusion, the results of the present study are in agreement with that of the pervious studies with regard to the high prevalence of anti­HCV IgG, anti­HCV IgM, HCV antigen and TNF­ga sin HCV infected patients. Also, there is an increased prevalence of TNF­ga sin positive anti­HCV IgG, anti­HCV IgM, and HCV antigen levels than in patients negative for these serological markers.The present results indicated that, TNF­ga swas detected in HCV patients, and it can be used as a marker to assess the activation of immune system in HCV infected patients.