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العنوان
Comparative study on the effect of gamma and UV­ rays on photooxidation of some natural furocoumarins and furochromones /
المؤلف
El­-Fadaly, Walid Mohamed Sabry.
هيئة الاعداد
باحث / ) وليد محمد صبري الفضالى
مشرف / حموده المتولى
مشرف / ايمان محمود الجندى
مشرف / ابوبكر عبدالمنعم رمضان
الموضوع
Skin diseases. Gamma and UV­ rays.
تاريخ النشر
2002.
عدد الصفحات
84 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Organic Chemistry
تاريخ الإجازة
01/01/2002
مكان الإجازة
جامعة المنصورة - كلية العلوم - Department Of Chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

The purpose of the present work was to exploit the characteristic features of furocoumarins and furochromones such as DNA intercalating, photoactive and some of them are widely used in the photochemotherapy of a number of skin diseases such as vitiligo and psoriasis, which can be isolated from: Heracleum sibiricum, Ammi visnaga and Myrrhis odorata. Comparative studies between our work under ?­rays and previous work using other conditions e.g. UV­light irradiation toward the following lines: The photooxygenation reaction of some furocoumarins and furochro­mones under ?­rays, which gave the same products as under UV ­light, in addition of some new products. ثEpoxidation reaction in presence of mCPBA under ?­rays gave the published epoxides with good yield, in addition of some new products, such as 1,4­dioxofuran derivative whereas, the epoxidation reaction in presence of hydrogen peroxide under ?­rays gave new products, such as epoxy of imper­atorin, visnagin and khellin.