الفهرس 
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Abstract
Fatty liver, or steatosis, is one of the important clinicopathological problems. It is characterized by excess fat accumulation in the liver, together with lobular and/or portal inflammation with or without fibrosis. There are apparently some factors acting in varying combinations, that are responsible for the fat deposition in the liver such as increased mobilization of fatty acids from adipose tissues, decreased utilization and increased synthesis of fatty acids in the liver, decreased secretion of fat from the liver and increased estrification of fatty acids into triglycerides (Murray et al., 1996). If not treated early, fatty liver may proceed to fibrosis with its dangerous sequelae. Therefore, attention is now made towards prevention and treatment of fatty liver by using variable substances. The aim of the present work, therefore, is to study the effect of fish oil, fenofibrate, phytic acid and vitamin ’E’ in the prevention and treatment of induced fatty liver by high fat, high sugar diet in rats.