الفهرس 
INTRODUCTION and Aim of the work.Only 14 pages are availabe for public view
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Abstract
This study aimed to evaluate the changes of nitric oxide, glutathione peroxidase, malondialdehyde and aminoterminal propeptide of type III procollagen in chronic liver diseases and to correlate these parameters with the pathogenesis and complication of chronic liver diseases. A total of 83 subjects were included in this study. Fasting blood sample was taken from each individual and analyzed for: a) Nitric oxide expressed in term of nitrate. b) Aminoterminal propeptide of type III procollagen. c) Malondialdehyde. d) Glutathione peroxidase activity. e) Liver function tests. All individuals were divided into group I: Hepatic cirrhosis, group II: Bilharzial hepatic fibrosis, group III: chronic viral hepatitis C, group IV: Hepatic malignancy and group V: Healthy controls. Results: There is a statistically significant increase of serum nitrate level in both hepatic cirrhosis and bilharzial hepatic fibrosis groups when compared with the healthy subjects, Meanwhile, there is a non significant difference of serum nitrate level in both hepatic malignancy and chronic hepatitis C groups when compared with healthy controls. There is a highly significant increase of serum PIIINP level in all studied hepatic patients when compared with control. There is a highly significant increase of serum MDA level in all studied hepatic groups when compared with healthy subjects. There is a highly significant decrease of glutathione peroxidase activity in all studied hepatic groups when compared with control.