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العنوان
Interventional radiologic techniques in management of hepatocellular carcinoma /
المؤلف
Abd-ElRahman, Ashraf Muhamed.
هيئة الاعداد
باحث / اشرف محمد عبدالرحمن
مشرف / مجدى محمد الرخاوى
مشرف / محمد عبدالوهاب على
مشرف / محمود عبدالشهيد راشد
الموضوع
Hepatocellular carcinoma.
تاريخ النشر
2001.
عدد الصفحات
272 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2001
مكان الإجازة
جامعة المنصورة - كلية الطب - الاشعة التشخيصية
الفهرس
Only 14 pages are availabe for public view

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from 286

Abstract

This study included 109 patients referred for locoregional management of surgically inoperable hepatocellular carcinoma, 98 males and 11 females with a mean age about 57.4 years. Of these patients, 45 were not suitable for any locoregional management and 64 patients were treated by various locoregional measures. Of these 109 patients; 21 patient were stage T2, 13 patients were stage T3 and 75 patient were stage T4. Of these 64 patients were submitted for locoregional management, 15 patients received PEI (alone or in combination with TAl or T ACE), 4 patients were treated by RF, 3 patients were treated by hepatic artery infusion and 42 patients with TACE. Transcatheter arterial chemoembolization and CT-lipiodol proved to be an important tool in both the initial staging and in management of HCC. CT¬lipiodol detected new masses in 10 patients (15.6% ) with subsequent change It in the patient stage in 4 patients (6.25%) and vascular invasion in 6 cases (9.4 %). We performed l’ACE guided by liver function. Selective and superselective embolization together with Gelfoam embolization were utilized whenever possible ( only in situation that guaranteed minimal risk to liver functions). Partial tumour response was achieved II patients (more than 50 % reduction in tumour sized) and complete tumour response in 7 patients. From our study it was found that patients with following criteria showed better response including: small tumours, nodular masses, single nodules, stage TI-T3 patients, highly vascular tumours that show dense lipiodol deposition, tumours less than 5 ern in diameter, absence of portal or hepatic vein invasion. While patients with the following criteria showed poor prognosis including: tumours more that 10 ern in diameter, infiltrative tumours, di ffuse in filtration, hypovascular tumours, multiple masses, stage T4 patients, portal vein invasion (especially its main trunk or its first order branches), I VC or hepatic vein invasion.