الفهرس 
Aim of the workOnly 14 pages are availabe for public view
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Abstract
Our study was carried at the Endocrine Unit OF Mansoura university Hospital aimed to investigate efficacy and kinetics and reproducibility of oral insulin was studied in healthy controls type I and type 2 diabetic patients Clinical problems in tile use o(insulin are: a) Requirement ofparentral adminstration b) Necissity offrequent adtninstration offast acting insulin per day c)Occurance. of hypoglycacmia during sleep or In the fasting (conditions with treatment hy slow acting insulin, insulin. being a polypeptide hormone, is digested and rapidly inacativated hycnzyems present in the alimentary tract, so that the oral route is ineffective means of administration in diabetes ntcllitus. Nevertheless. absorption ofinsulinjrotn the small uucst uu: resulted in a lowering of blood glucos, has been shown to occur in animals in the first few days after birth due to deficent gasrointcstinal digestive enzymes pierce etal 1964 and when pancreatic enzymes were inactivated in cxperimental using disopropy-fluorophosphatc and soya bean inhibitors Danforth and Moore.1959.)