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Abstract The discovery of hepatitis C virus (HCV) is the major breakthrough in the history of non-A non-B hepatitis however, it has become increasingly evident that there may be an additional viral agents which cause community acquired or post-transfusion NANB hepatitis. A recently isolated virus belonging to Flaviviridae family yet distinct trom HCY, this virus (GBV-C)isolatedbySimmonsetal, (1995) and so called hepatitis G virus by Linnen et ai, (1996) are two isolates of the same vuus. Little is known about the epidmiology and the pathogenicity of this newly discovered virus, inspite of large number of’studies carried on the GBV-C so far, it is still unknown weather the virus ca!1 detclmine liver disease in human. Hepatitis viruses may interact with each other, this interaction may be synergistic, antagonistic or additive to modify the clinical picture. The aim of this work is to detect the prevalence ofGBV-c in patients with hepatitis B, hepatitis C and schistosomiasis then, to evaluate the impact of this co-infection on the course of the disease. |