الفهرس 
Introduction and Aim of The WorkOnly 14 pages are availabe for public view
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Abstract
Liver cirrhosis is a chronic and common disease, that leads to destruction and distortion of hepatic parenchyma and architecture. Liver cirrhosis represents the end stage of a variety of chronic liver diseases like HBVandHCV. The aim of this work was to study the DNA ploidy changes of hepatocytes in liver cirrhosis; assessment of liver cell dysplasia; and to find the relationship between HBV and HCV serological markers and the occurrence of liver cell dysplasia and DNA ploidy changes. This work was conducted on 56 male patients presented clinically with liver cirrhosis at Mansoura University Hospital, and they were subjected to: 1. Thorough history taking and full clinical examination. 2. Routine laboratory investigations including: Complete blood picture, some liver function tests. 3. Serological tests (hepatitis viral markers).i 4. Abdominal ultrasonography. 5. Upper gastroendoscopy. 6. Segmoidoscopy and examination of rectal mucosal biopsy. 1’. Percutaneous liver biopsy histopathological examination. { 8. DNA flow cytometry of fresh hepatic tissue.