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العنوان
Genetic influences on airway inflammation in bronchial asthma /
الناشر
Ali Mahmoud Ali Gebriel,
المؤلف
Gebriel, Ali Mahmoud Ali.
هيئة الاعداد
باحث / على محمود على جبريل
مشرف / محمد مصطفى حافظ
مشرف / طارق الدسوقى
الموضوع
Genetic influences-- bronchial asthma.
تاريخ النشر
1999.
عدد الصفحات
146 p. ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/1999
مكان الإجازة
جامعة المنصورة - كلية الطب - طب الاطفال
الفهرس
Only 14 pages are availabe for public view

from 164

from 164

Abstract

Asthma is a common disorder whose prevalence in the population estimated to range from 3% to 50/0. Bronchial asthma is an inflammatory airway disease associated with intermittent respiratory symptoms, bronchial hyperresponsiveness and reversible airway obstruction and is phenotypically heterogeneous. The airflow obstruction of asthma is due to combination of bronchial smooth muscle qontraction, mucosal edema and inflammation, and viscid mucus secretion. These pathophysiologic events cause asthma as they lead to reduction in small airway diameter and increase in airway resistance which make it difficult for inspired air to escape the lungs. These changes lead to reduction in forced expiratory volumes and flow rate, and hyperinflation of lung with air trapping. The increase in the work of breathing creates a sense of breathlessness.