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Abstract Hepatitis C is a major public health problem. Unlike hepatitis A and B, there is no vaccine againest hepatitis C, and HCV infection progresses slowly over 10 to 20 years with the majority of cases being asymptomatic untill late in the course of disease. High percentage of patients will progress to chronic active hepatitis with cirrhosis even hepatocellular car¬cmoma. On the bases of recent epidemiological studies, it is estimated that anti-HCV prevalence ranges from 4% to 38% in different governorates in Egypt. The aim of this work is to estimate anti-HCV prevalence among blood donors and travellers to Arabian Gulf Countries in Dakahlia governorate, besides study of some risk factos for hepatitis C infection through fulfilling a questionnaire which was designed for estimation of the level of knowledge, attitude and practice of the studied population towards hepatitis C. This study was done through meeting of a randomly chosen 1162 individuals with mean age was (29.3 ± 7.6 year), out of them 964 were blood donors, and 198 travellers to the Arabian Gulf countries, for each of them fulfilling a questionnaire, and examination of blood sample using 2nd generation ELISA was done. Prevalence of anti-HCV was found to be (19.8%) among the studied population, this prevalence decreased to be (18.4%) among blood donors, and increased significantly to (26.8 %) among travellers to Arabian Gulf countries, this is due to ex- |