الفهرس 
INTRODUCTION AND AIM OF THE WORKOnly 14 pages are availabe for public view
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Abstract
This work has been carried out on umbilical cord blood of 520 newborns. The samples were taken randomly from the obestetric Departments of Mansoura University Hospital, Mansoura General Hospital and Manzala Central Hospital. They were representing various social classes, religions and both sexes. An ’cord blood specimens were obtained at the time of delivery of these newborns, 504 were fullterm having gestational ages ranging between 37 and 42 weeks, whereas the remaining were premature with gestational ages ranging between 28 and 36 weeks. All of them were normal healthy and product ’of non complicated pregnancy and delivery. All the neonates are assessed for general examination. Although the primary focus of newborn hemoglobinopathy screening is to identify patients with sickle cell disease, our preliminary data suggest that patients with other hemaglobinopathies will also benificial. Cord blood screening has been proved to be both practical and effective and that it can significantly reduce the mortality of sickle cell disease when linked to a comprehensive clinical programmes with a strong family education component. We have found a total frequency of lib (s) positive carriers of about 1.72% which almost conforms with what was found previously by Marilyn et al. (1987) of 2% in Mediterranean area. However based on our results, in our community we expect minimum incidence of about 1215 affected newborns Iyear with sickle cell anaemia. In our work we reported afrequency of about 1.9% positive Hb Bart’s carriers among the newborn samples.