الفهرس | Only 14 pages are availabe for public view |
Abstract This study was done to evaluate the changes which may occur in the cervix uteri in patients affected by schistosomiasis. Evaluation was done clinically, colposcopically and cytohistopathologically. In addition to these an immunohistochemical study was done to examine the inflammatory and cellular immune responses elicited by schistosomiasis in the cervix. This study was conducted on two groups of patients attending the gynecology and/or medical out-patient clinics in Mansoura University Hospital. These groups are the study group and the control group. The study group included 170 patients affected by schistosomiasis as proved by the detection of bilharzia ova in their urine and/or stool or by a positive rectal snip for schistosomal infestation. Rectal snip was done if urine & stool analysis were repeatedly negative for bilharzia ova. The control group included 85 patients assumed to be free from schistosomiasis by repeated negative urine and stool analysis and by negative reet,l snip. Both groups were comparable as regards age, age at marriage, parity and socioeconomic standard. of both groups were pregnant, lactating or having any clinical general disease that could influence the results of the study. were under radiotherapy, chemotherapy or immunosuppressive treatment. had received contisone, local or systemic antibiotics or had cervical cauterization at least for one month before inclusion into the study. had sexual intercourse or vaginal douche in the last 24 hours . . Every patient was subjected to clinical, cytological, and colposcopic evaluation. Endocervical curettage, (ECC), was done for every case. Colposcopically directed punch biopsy was taken from any case showing abnonnal colposcopic findings and from areas showing maximal inflammation. |