الفهرس | Only 14 pages are availabe for public view |
Abstract This study was conducted on a total of 46 cases including 20 diabetic impotent patients ,16 potent diabetics and 10 potent non diabetic cases. All cases were subjected to thorough history taking, general and local genital examination, estimation of serum testosterone and prolactin levels and post prandial blood glucose level. Measurement of penile sensation by the biosthesiometer , estimation of penile brachial index (FBI), and pharmacocavernosometry utilizing the redosing technique were done, to all cases. The diabetic impotent cases were subdivided into three groups according to the results of pharmaeoeavernosometry : Group (1): Included 7 cases who achieved complete trabecular smooth muscle relaxation, evidenced by a linear relationship between the maintenance flow rate and intracavernosal pressure after injection of 60 mg papaverine. Group (2):Included 7 cases who achieved linear relationship between the maintenance flow rate and intracavernosal pressure after injection of 60 mg papaverine + 20 jag prostaglandin El. Group (3 ) Included the remaining 6 cases in whom the linear relationship between the MF and ICP could not be established due to the persistent tmlure of induction inspite of the increase of the vasoactive dose to 60 mg papaverine + 20 ug PGE 1 + 1 mg phentolamine . However, the complete trabecular smooth muscles relaxation was evidenced by cavernous electromyography that revealed the presence of an isoeiectric line after injection of this dose . Also there was an electric evidence of smooth muscle degeneration before injection that is possibly one of the causes of veno-occlusive dysfunctions in this group. |