الفهرس | Only 14 pages are availabe for public view |
Abstract Malignant lymphoma - is considered the third most frequent neoplastic disease (El-Bolkainy et aL, 1991) in Egypt. Haemostatic complications are the second most common cause of mortality in lymphoma (Luzzato and Schafer, 1990). These may be presented either by haemorrhagic or thrombotic manifestations. The mechanism of this are multifactorial,, either due to quantitative or qualitative platelet abnormalities, abnormalities of coagulation cascade,, or impaired fibrinolytic system (Ratnoff, 1989). So, we planned this work to clarify the role of fibrinolytic system in the development of thrombotic manifestation in patients with lymphoma. In order to achief this goal, this study were carried out on 74 patients with mah ant lymphoma, 20 cases at the time of diagnosis and 54 cases after complete remission either by chemotherapy, radiotherapy or both as well as 20 apparently healthy individual as control group. Patients were diagnosed by clinical findings peripheral hemogram, bone marrow aspiration and diagnosis is confirmed by histopathological. examination of the affected lymph nodes or spleen. According to histopathological examination of the affected lymph nodes, the patients were grouped into:- |