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Abstract Pe brile c onvul sions are the s.i.ng Le mo s t c ornmon t clin- ically important complication of fever (.Lorin, 1982). A seizure occuring with a temperature of J8°e or moret in the absence of detectable infection of the central nervous sys¬, I ,J, q). , j temt is termed a febrile convulsion (Forfar In a clinical, electroenoephalic and genetic study of patients with febrile c on vuLs i ori , Ilafe z t . (l " ~ "H3J) proved the suscaptibili ty to be due to polygenic .inhe r Lt ano e wf. th a heritability 69.4%. In last years some reports nave been pu bLt.nhe d concern- ing disorders of humoral immunity .i.n e p i.Le pt i.c and febrile convulsion patients (Ettlinger and Lowrie, lY76; Fontana et al., 1976). However nothing was reportea in the available literature about cell mediated immunity and HLA-antigens ass- ociation in patients with febrile convulsion. This work studies the relation between i" ~ "nunodeficiency and the pathogcmesis of febrile convulsions and if there is any linkage or association with HLA-antigenE.. |