الفهرس 
Introduction
Renal TransplantationOnly 14 pages are availabe for public view
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Abstract
Renal transplantation is the preferred mode of renal replacement therapy for end stage renal disease because of long term survival and better quality of life when compared to dialysis. The early post transplantation period is the most critical time and is complicated by surgical and medical renal problems. The most common medical causes for delayed graft function are AR or ATN. Also CsA nephrotoxicity can simulate AR in clinical symptoms. For long time laboratory tests and renal biopsy were the preferred mode for diagnosis of post transplant complication. Given the prolonged survival now possible for renal transplant recipients because of newer medical and surgical techniques, it is increasingly important to use non invasive modalities of for screening these patients and evaluating their complications. Radionuclide imaging, US and Doppler were introduced. MRI provides excellent pre and post contrast anatomic images, it has multiplannar capability and there is no need for iodinated contrast material or ionizing radiation exposure. Dynamic MRR offers a promising technique to provide both morphological and functional changes in renal transplant recipients. This study was conducted on 60 patients who underwent renal transplantation in urology and nephrology centre in Mansoura from January 2003 to December 2004. 27 patients were taken as a control group, and 33 patients with post transplant complications. Post contrast dynamic MRI and renal scintigraphy was performed for all patients renal biopsy were performed to patients with complications and was considered the gold standard. The results of MRR were compared with RNS and biopsy. MRR was able to produce SI, time curves similar to that of RNS with the advantage of higher spatial resolution and combining more morphological and functional evaluation of transplanted kidney in one examination without exposure to ionizing radiation. MRR showed sensitivity of 80% specificity of 73% and accuracy of 78.7% in detection of rejection as it is the most dangerous complication of renal transplant recipients. While MRR was sensitive in detection of ATN in 3 out of 4 cases. In diagnosis of CSA nephrotoxicity it was able to detect 5 out of 6 cases. Also MRI was able to estimatic GFR with good correlation with GFR detected by isotope study. from this study we conclude that MR renography is a potential feasible alternative to radionuclide renography.