الفهرس 
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Abstract
In the present work two experiments were conducted to study the toxic effects of AFB1 with levels (0,100 and 200 ppb) on Oreochromis niloticus fingerlings (average weight 13.00 gram). As well as, to examine the effect of some adsorbents agents with levels (0, 1 and 2%) to detoxify the toxic effects of AFB1 on fish for 8 weeks in each experiment. The obtained results showed that AFB1 led to severe clinical lesions and postmortem symptoms of the afltoxicated fish, significant (p<U+2264> 0.01) decrease in growth performance parameters, survival rate, feed intake and nutrients utilization of fish, dray matter, crude protein and energy content of fish carcass, hemoglobin concentration, red blood cells count and uric acid. As well as, decrease in dray matter and increase in ether extract of the fish liver (fatty liver) were recorded. However, AFB1 caused significant (p<U+2264> 0.01) increase in corrected mortality rate, organs indices (HSI,KSI,SSI and GSI), feed conversion ratio, ether extract (fat) and ash of fish carcass, white blood cells count, alkaline phosphatase, glutamic oxaloacetic transferase and glutamic pyruvic transferase activities in aflatoxicated fish. On the other side, residues of AFB1 (ppb) were found in the whole body of the aflatoxicated fish directly at the end of the experiment and tended to decrease after freezing periods. As well as, severe histological alterations were recorded in livers, kidneys, intestines and gills of the aflatoxicated fish. Also, the results indicated that the effects of either adsorbents namely, egg shell and shrimp waste at levels of 1 and 2%, respectively, were useful to reduce the toxic effects of AFB1 on O. niloticus fish via adsorbing the toxin from the fish diets.