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Abstract Pancreatic cancer is an aggressive form of cancer and is currently the fourth leading cause of cancer-related deaths worldwide. Despite advancements in diagnosis and treatment, the one-year survival rate remains low at approximately 19%. To improve the quality of life for these patients and prevent cancer recurrence, the Enhanced Recovery after Pancreatic Surgery (ERAPS) program has been developed. This protocol, based on evidence, aims to standardize and optimize perioperative care to reduce surgical trauma, organ dysfunction, and physiological stress. It has also been shown to decrease the incidence of complications, shorten hospital stays, and increase patient satisfaction while reducing healthcare costs. Since its establishment in 2012, the ERAPS program has undergone evaluation for 27 different components, with five of them having the highest level of evidence. This includes measures like maintaining normal body temperature, continuous pain management, following antibiotics and thromboprophylaxis protocols, and providing preoperative nutritional support for patients with severe weight loss (≥15%). The ERAPS society encourages further research to improve patient’s compliance and outcomes and also, validate the benefits of the currently recommended updates. |