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Abstract The role of iron in the formation and functioning of erythrocytes, and to a lesser degree of white blood cells, is well established. However, the relationship between iron and platelets is less documented. Physiologically, iron plays an important role in hematopoiesis including thrombopoiesis. Hepcidin levels are reduced in patients with iron deficiency (ID). Therefore, measurement of hepcidin levels may enable the determination of iron requirements and be an accurate indicator of physiological ID. Methods: cross sectional study conducted with 100 patients were equally divided into two groups: 50 patients with Thrombocytopenia and 50 patients with Thrombocytosis, the two groups were further subdivided into four subgroups categorized by iron profile (Low vs. Normal). comparison of iron parameters and hepcidin level among the studied group. |