الفهرس 
CHRONIC KIDNEY DISEASEOnly 14 pages are availabe for public view
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Abstract
ABSTRACT
Background: Neuro-development deficits have long been recognized as a major complication of pediatric chronic kidney disease (CKD). Some of this impairment has been attributed to the possible effects of kidney failure: uremia, anemia, hypertension and malnutrition,However, no published papers specifically examining the prevalence of ASD within the pediatric nephrology population.
Aim and Objectives: This work designed to evaluate the association of autism spectrum disorder with pediatric chronic kidney disease, Subjects and methods; This study was designed to be an Observational Cross Sectional study One hundred children with chronic kidney disease not on dialysis were recruited from the nephrology Pediatric Clinic, Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt, during their follow up visits.
Patients and Methods: This study was designed to be an Observational Cross Sectional study One hundred children with chronic kidney disease not on dialysis were recruited from the nephrology Pediatric Clinic, Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt, during their follow up visits full Demographic data collected and detailed developmental history and family history of learning problems, psychiatric disorders and social disability. Antenatal , natal, and postnatal histories Family history of learning problems, psychiatric disorders and social disability. Antenatal , natal, and postnatal histories.and history of Renal disease (etiology, onset, duration, compliance to treatment) thorough clinical examination to Assess eligibility of inclusion, and, exclusion criteria, and Examination for dysmorphic features or neurodevelopment findings of clinical syndromes associated with ASD then Psychiatric evaluation based on the Clinical Interview For Children And their caregivers to Assess Psychosocial function by using pediatric symptoms check list then Diagnosis of ASD Using DSM-5 diagnostic criteria then Assess the severity of autism using the Arabic version of the Childhood Autism Rating Scale (CARS)
Result; no autism is detected in our study group but behaviour change is demonstrated in 9 percent of study group Conclusion; autism spectrum disorder need to be evaluated in large study group with mainly congenital kidney disease .
Conclusion: Patient with chronic kidney disease even not on dialysis has sign of significant behaviour change need to be more investigated. Despite no positive result with autism in our study it should be investigated in large study group with mainly congenital anomalies of kidney disease.