الفهرس 
Thyroid nodulesOnly 14 pages are availabe for public view
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Abstract
Thyroid nodules are very common clinical entities, their incidence
increases with age and they have a variable appearance from the solid to the
cystic nature, however, most of the nodules tend to have a benign nature and
the malignancy has been reported in less than 5% of the nodules
Because of the suspicion of malignancy, thyroid nodules require a
detailed examination and Investigation. Clinical examination,
ultrasonography (US), radionuclide scintigraphy, and fine-needle aspiration
cytology (FNAC) are the common methods to evaluate thyroidal nodularity.
The systemic inflammatory response is considered to promote
different stages of cancer development and invasion.
The neutrophil-to-lymphocyte ratio (NLR) is commonly accepted as a
biomarker of systemic inflammation. As a result, it serves as a predictor of
metastasis and poor prognosis in a variety of malignancies, including breast,
colon, head, neck, and thyroid cancers
The aim of work:
The aim of work is to determine if preoperative neutrophil-tolymphocyte ratio can be used as a predictive factor for thyroid cancer in
patient with thyroid swelling or nodule with TIRADS classification (3, 4, 5)
and who will undergo thyroid surgery.
To elucidate this aim, 50 patients of thyroid swelling or nodules who
are decided to undergo surgery were included in the study.
The main results:
In the current study, the mean age of the studied patients was 45.947
years with a range between 18-64 years with female predominance 36 cases
to 14 males
According to the nature of the lesions, there were 42% of the studied
cases were benign lesions and 58% were malignant
There were two (4.0%) patients had positive family history and11
(22.0%) patients had history of other endocrine disorders .
There was a significant relation in between neutrophil-to-lymphocyte
ratio and lymph node metastasis.
The sensitivity of neutrophil-to-lymphocyte ratio in prediction of
thyroid cancer was 83% and the specificity was 73%.