الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
worldwide, and it results from a dysregulation of the systemic inflammatory response to infection. Identifying patients, who are at a high risk of poor outcomes, in the early stage of sepsis, is vital for timely and adequate intervention.
Objective: Evaluation of the prognostic benefit of platelets to lymphocytes ratio derived from the blood sample drawn on the day of ICU admission in sepsis severity assessment.
Patients and Methods: A total of 70 patients were subjected to selective investigations included complete blood count and arterial blood gases. As regard mortality distribution cases were divided into survivors (40 cases) and non survivor (30 cases). Primary outcome was hospital mortality rate and secondary outcome measures were mean arterial blood pressure, temperature, heart rate, total leuococytic count and serum lactate.
Results: There was statistically significant lower mean value of platelets to lymphocytes ratio in non-survivor group comparing to survivor group. ROC curve analysis proved good discriminating power of the platletes to lymphocytes ratio between non-survival and survival where accuracy 85.7% at cutoff point ≤ 96.7 with sensitivity 90% and specificity 82.5%. There was a statistically significant higher mean value of WBC (t/ccm) and serum lactate (mmol/L) in non-survivor group compared to survivor group.
Conclusion: PLR to be a promising biomarker that can be readily integrated into clinical settings to aid in the prediction and prevention of sepsis mortality.