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Abstract Background: Non-arteritic anterior ischemic optic neuropathy (NAION) is an ischemic change that affects the anterior part of the optic nerve head (optic disc). Fundus fluorescein angiography (an invasive investigation) and visual field perimetry are used for the diagnosis of NAION. Optical coherence tomography angiography (OCTA) is an advanced new non-invasive modality for assessment of vascularity of tissues at different retinal levels. Objective: aim of the study was to analyze the optical coherence tomography angiography findings in acute NAION patients (at 0, 6 and 12 weeks from onset). Patients and Methods: This study included a total of 30 patients diagnosed with acute NAION attending at Ophthalmology outpatient clinic of Fayoum University Hospitals. OCT and OCTA was done for all subjects and control group with Optovue, Inc., Fremont, CA, USA. Results: showed a significantly lower NFLT, CMT and GCC in diseased eyes after resolution of edema. Vessel density was significantly reduced in most DISC and peripapillary sectors of NAION-affected eyes (except for the deep macula and FAZ). Conclusion: We can depend on quantitative differences in perfusion density measured by OCTA in follow-up of progression in NAION cases. Keywords: Optical coherence tomography angiography, non-arteritic anterior ischemic optic neuropathy, superficial peripapillary plexus perfusion density. |