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العنوان
ASSESSMENT OF MYOCARDIAL VIABILITY BY CARDIAC MAGNETIC RESONANCE FEATURE TRACKING AT REST AND DURING STRESS BY LOW-DOSE DOBUTAMINE /
المؤلف
Sayed, Abdulrahman Emam Eldeen,
هيئة الاعداد
باحث / عبدالرحمن إمام الدين سيد حمدان
مشرف / أسامة حارث عبداللطيف
مناقش / رجب هانى محمد
مناقش / حسام الدين جلال أحمد
الموضوع
Diagnostic Radiology
تاريخ النشر
2024.
عدد الصفحات
130 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
الناشر
تاريخ الإجازة
26/6/2024
مكان الإجازة
جامعة أسيوط - كلية الطب - Department of Diagnostic Radiology
الفهرس
Only 14 pages are availabe for public view

from 130

from 130

Abstract

Cardiac magnetic resonance (CMR) is the preferred imaging method for assessing myocardial viability in patients with chronic cardiac ischemia. Recently, CMR-FT has emerged as a new technique that quantitatively estimates myocardial strain, providing precise information on regional myocardial function, scar tissue, and viable myocardium. Dobutamine, a synthetic catecholamine, enhances myocardial contractility at different doses and has a positive chronotropic effect, increasing myocardial contractility and heart rate. Intravenous dobutamine infusion has been used to increase myocardial contractility during CMR examination.The study involved 50 patients with known ICM who underwent a cardiac magnetic resonance (CMR) study before and after LDD administration. A healthy control group was analyzed for normal values at rest. The ”ICM” group underwent feature tracking analysis after LDD, and segments with improved strain values were identified as viable after comparison with DGE. The study found that segments devoid of or with less than 50% fibrosis showed significant increases in Ecc, Err, and Ell strain values with LDD, opposite to those with more than 50% fibrosis that showed no significant improvement in strain values, suggesting that MR FT is a valuable tool for myocardial viability detection With further research and validation, feature-tracking MRI could become an indispensable tool in managing ischemic patients, leading to better prognoses and improved quality of lifeThe study aimed to evaluate the use of MR-FT in assessing myocardial viability in ischemic patients with chronic LV systolic dysfunction. However, it did not include post-revascularization follow-up data and did not assess intra-observer and inter-observer variability.