الفهرس 
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Abstract
Introduction: Non-carious enamel loss is becoming more prevalent due to modern dietary habits which lead to increased levels of dentinal hypersensitivity (DH). DH, specifically in cervical area, manifests through dental abrasion, dental erosion, occlusal trauma, etc. When the dentin is exposed, external stimuli can cause excessive pulpal pain response. Dental adhesives/restorations and desensitizers have been developed for obliteration of dentinal tubules and treatment of DH.
Aim of the study: to clinically evaluate the effectiveness of a glutaraldehyde-based desensitizer (Gluma™ Desensitizer Heraus-Kulzer, Hanau, Germany) vs a conventional universal bonding agent (Scotchbond™ Universal Adhesive) in reducing cervical dentin hypersensitivity over a 6-month follow-up period.
Methods: 14 patients having a minimum of two contralateral teeth with cervical dentin hypersensitivity were allocated for a split-mouth, double blind, randomized controlled trial. Each Patient received glutaraldehyde desensitizing agent (Gluma™ Desensitizer; Heraus-Kulzer, Hanau, Germany) on one side vs Scotchbond™ Universal Adhesive on the other side. A total of three desensitization sessions were performed at 5 days interval for each patient. For assessment of hypersensitivity levels, air blast and tactile (Visual Analog Scale) sensitivity scores were evaluated at baseline (T0), immediately after each desensitizing session (T1,T2,T3), and at the 1st (T4), 3rd (T5), 6th (T6) months of follow-up.
Results: Both agents reduced dentin hypersensitivity significantly over the course of the study. For Gluma group, mean airblast-VAS scores were reduced from 5.0 ± 2.3 at baseline to 1.1 ± 1.3 at T6 with a total percent reduction of 78.8%, and Scotchbond scores were reduced from 5.1 ± 2.3 at baseline to 0.9 ± 1.1 at T6 with a total of 84.75% percent reduction. The difference between percent reduction in air blast VAS scores for both groups was not statistically significant (p=0.493). On the other hand, Probe sensitivity VAS scores reduced from 1.0 ± 2.3 to 0.1 ± 0.2 with 19.71% total pain reduction for group I, and from 1.2 ± 2.5 to 0.1 ± 0.3 with 39.17% total pain reduction for group II, showing statistically significant difference between the groups.
Conclusions: Gluma desensitizer and Scotchbond Universal Adhesive resulted equally in a reduction of pain intensity for patients with Dentin hypersensitivity. No advantage was detected for the use of one material over the other.
Keywords: Cervical dentin hypersensitivity, glutaraldehyde, desensitizing agent, dentin bonding agent.