الفهرس 
GLOMERULONEPHRITISOnly 14 pages are availabe for public view
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Abstract
Results: We have analyzed the data of 1851 renal biopsies, with a mean age of 38.43 ± 14.83. 52.4% of the study population are males, and 47.6% are females. Hypertension was present in 71.9% of the patients. Nephrotic syndrome was the most common clinical presentation at the time of biopsy, occurring in 37.5% of the cases. Primary glomerulonephritis was the most common renal pathology diagnosis, accounting for 47.1% of the cases, followed by secondary glomerulonephritis (27.5%) and vascular diseases (21.5%). Hypertensive nephrosclerosis was diagnosed in 18.7% of the patients. There were significant differences in the diagnosis of renal pathology among different age groups. Lupus nephritis was the most common diagnosis in the age group of 18-39 (24.6%), while hypertensive nephrosclerosis was the most common in the age groups of 40-59 (27%) and ≥60 (25.6%). There were also significant differences in the clinical presentation at the time of biopsy for most renal pathology diagnoses. For example, membranous GN was the most common renal pathology diagnosis among patients presenting with nephrotic syndrome (30.3%). Lupus nephritis was the second most common renal pathology diagnosis, accounting for 56.2% of cases presenting with nephritic syndrome. In addition, 41.3% of the lupus nephritis cases were classified as class IV, with a median activity and chronicity index of 10/24 and 4/12, respectively. There was a significant relation between lupus nephritis classes and laboratory data.
Conclusion: Renal biopsy most commonly presents with nephrotic syndrome. Primary glomerulonephritis is the most common diagnosis, with membranous GN being the most prevalent. Lupus nephritis is the most common secondary glomerulonephritis, mostly presented with nephritic syndrome, with class IV being the dominant type