الفهرس 
AcknowledgementOnly 14 pages are availabe for public view
 |  | from | 80 |  |  |
| | | from | 80 | | |
Abstract
Management of lymphoma depends on accurate staging of lymphoma. PET/CT is an effective tool for evaluation of extranodal lymphomas .it is essential for detection, accurate staging, and planning of management of lymphoma
PET/CT study offers a chance for complete assessment for extranodal lymphomatous infiltration and allows proper staging of lymphoma and enables accurate detection of more extranodal lymphomatous infiltration that help in up or downstaging the disease.
PET/CT is superior to CT in detecting extranodal disease in the abdomen, especially in the spleen and liver, and BM based osseous infiltration
PET/CT scan showed higher sensitivity, specificity, and accuracy which led to alteration of disease staging with marked effects on the decision of treatment regimens.
There is positive correlation between SUVmax of the extranodal lesions and hottest LN. Organ involvement and FDG avidity greatly depends on histopathological subtypes
PET/CT fusion images can affect the clinical management plan by detection of extranodal lymphomas with lymphoma staging modification
Identification of extranodal lymphomatous involvement is prognostically important in management . PET-CT is a hybrid technique that provides both anatomical and functional data.
Many lymphomas are potentially curable with their prognosis depends on the stage and histological type . CT scan used to be the cornerstone of imaging in lymphoma and was playing a crucial role in staging. Currently, the advances in molecular imaging with18F-FDG PET/CT scan have facilitated the diagnosis, staging, and response assessment in lymphoma patients . Integrated PET/CT offers the advantage of combining functional and anatomical information as well as better attenuation correction
18F-FDG PET/CT scan has a better diagnostic performance, represented by sensitivity, specificity, and accuracy, than CECT scan in the initial assessment of lymphoma regarding its nodal and extra-nodal lesions that could lead to alteration of disease staging which in turn markedly affecting the decision of treatment regimens.
early assessment of response to therapy by PET/CT is as an important prognostic parameter which is useful for the identification of patients with an increased risk for relapse or progression.