الفهرس 
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Abstract
Aim of the Study: This study was carried out to clarify the effect of combining fluoride
or CPP-ACPF with self-assembly peptides in comparison to the remineralizing potential
of self-assembly peptides on their own.
Null Hypothesis Tested: First, there is no difference in the remineralizing potential
between self-assembly peptides, fluorides, and CPP-ACPF. Second, the combination
between fluoride, CPP-ACPF and self-assembly peptides will not have any effect on
remineralization of artificial carious lesions.
Materials:
1) Demineralizing Solution.
2) Artificial Saliva.
3) Remineralizing Agents: Bifluorid 10 (fluoride-based varnish), MI Varnish (CPPACPF-based varnish), and Curodont Repair (self-assembly peptide-based
remineralizing agent).
Methodology:
1) Teeth selection:
Sixty sound freshly extracted molar teeth were collected and inspected under a
stereomicroscope to exclude any enamel defects, and they were cleaned.
2) Grouping:
Specimens were randomly allocated into two equal groups of 30 specimens each
according to use of the biomimetic material:
a. Control group (B0): specimens did not receive biomimetic material,
b. Test group (B1): specimens were treated with Curodont Repair.
Each group was further subdivided into 3 subgroups 10 specimens each according
to the remineralizing material used; either artificial saliva, fluoride (Bifluorid 10), or CPPACPF (MI Varnish).
Summary
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3) Specimens Preparation:
Molars were sectioned horizontally 2 mm below the cemento-enamel junction;
crowns then were embedded in cylindrical acrylic resin molds with the buccal surfaces
facing upwards. The buccal surfaces were flattened using finishing and polishing disks.
After that, a 4 × 4 mm window was created on the buccal surface of each specimen and
the whole remaining enamel surface was covered by an acid resistant nail varnish