الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
ROP continues to rank among the most common causes of blindness in children. Premature infants are the primary patients, as they are more likely to be clinically unstable and prone to problems and anesthesia-related side effects during examinations or treatments.
Premature neonates require one or more ophthalmological examinations using BIO. Neonates continue to undergo considerable pain, despite the application of conventional analgesia via eye drops of topical anesthesia and/or oral sugar solution.
The aim of the current study was to determine the effect of benoxinate topical anesthetic eye drops on reducing the pain in preterm infants undergoing screening for ROP using the PIPP score.
The current study included a total of 77 neonates who underwent screening for ROP twice, of which 44 neonates were examined with tears substitutes eye drops in first examination and benoxinate eye drops in second examination, and other 33 neonates were examined with benoxinate eye drops in first examination and tears substitutes eye drops in second examination.
The current study revealed the following outcomes:
• No significant differences were recorded between both groups regarding all demographic features.
• No statistically significant differences were recorded between both groups as regards PIPP score during all the stages of examination and after examination.
• Both groups demonstrated insignificant differences as regards oxygen saturation and heart rate.
Conclusion:
In the context of preterm infants undergoing screening for ROP, benoxinate topical anesthetic eye drops have no additional advantage over placebo (tears substitutes). They cannot be relied on as a sole factor to control infant stress and additional measures should be considered during examination.