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Abstract Headache is considered one of the major complaint in everyday life for many people. Most people will suffer from headaches at some point or another throughout their lives. Pain in the head or face is the main symptom of a headache. Headaches come in a variety of forms, with tension headaches being the most prevalent. While the majority of headaches are not dangerous, some types may indicate a serious underlying condition. Many countries became aware that headache disorders represent an important threat to public health. In spite of the discrepancies among different studies, the overall picture resulting from evaluationof thepatterns that we find in central electrophysiological maneuvers clearly confirms that primary headache disorders can cause these patterns which may help us not only in the diagnosis of different types of primary headache disorders , but also in understanding the pathophysiology of different headache disorders. According to changes in visual evoked potentials in migraine, many studies found that the SS-VEP frequently has a larger amplitude in both types of migraine although some studies showed Reduction in SS-VEP response. In conventional VEP, many studies showed higher VEP amplitudes compared with controls. Deficient VEP habituation to repeated stimuli was reported an most of studies. As regard changes in VEP in Tension headache patients, most of the results have found that there is No significant changes in P100 latency and amplitude. According to changes in BAEP in migraine, many results found that latencies are greater and more asymmetric in migraineurs. In contrast minority of studies found that there are no changes in BAEP in146 migraineurs as regard short, middle and long latencies as well as habituation. In contrast, all of the results of BAEP in Tension headache patients showing that there are no changes in BAEP. Regarding changes in blink reflex in migraine, most of the results found there is no changes in conventional BR in migraineurs, the same findings were found in Nociception-specific blink reflex although some studies found that R2 amplitude was noticed to increase and latency decreased on the side of the pain in migraine patient during attacks. Lack of habituation in migraine was the hallmark finding when studying habituation. In contrast, some of the results of BR in Tension headache patients showing that there are no changes in while some showed that ipsilateral and contralateral R2 values are extended. in Nociception-specific blink reflex ther were no changes again. Changes in QEEG in migraine during headache attacks range from slowing and reduced alpha rythm to decreased interictal EEG coherence. In preectial phase, an increase in beta-ERD (Event Related Desynchrinization) as well as increased alpha range flicker along with sluggish and asymmetric background activity appeared. In tension headache, Spikes, sharp waves, slow waves, and an increase in theta activity are some examples of abnormalities. |