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العنوان
Role of Optical Coherence Tomography Angiography in Assessment of Age-related Neovascularization Response to Intravitreal Anti-vascular Endothelial Growth Factor /
المؤلف
Omar, Mohamed Salah Ahmed
هيئة الاعداد
باحث / محمد صلاح احمد عمر
مشرف / أسامة محمود البسيوني
مشرف / حسين الح الدين النحاس
مشرف / طارق محمود رضوان
مشرف / ميرفت الشبرواي الغريب
الموضوع
Ophthalmology.
تاريخ النشر
2023
عدد الصفحات
127 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
طب العيون
تاريخ الإجازة
1/1/2023
مكان الإجازة
جامعة قناة السويس - كلية الطب - Ophthalmology
الفهرس
Only 14 pages are availabe for public view

from 155

from 155

Abstract

Age-related macular degeneration (AMD) is a medical condition which may
result in blurred or no vision in the center of the visual field. Early on there are
often no symptoms. Over time, however, some people experience a gradual
worsening of vision that may affect one or both eyes.
Spectral domain optical coherence tomography SD-OCT is a noninvasive
imaging technique, able to visualize structural changes of the neuro sensory retina
and the retinal pigment epithelium RPE. OCT is used to support the initial
diagnosis of CNV obtained from FA and ICGA and to detect early signs of CNV
activity, such as subretinal fluid, intraretinal cystoid spaces, and pigment
epithelium detachment PED.
Intravitreal injection is the standard method of administration, of antivascular
endothelial growth factor Anti-VEGF which block its interaction with
receptors on the endothelial cell surface and so retard or reverse vessel growth.
They have become the predominant means of treatment for CNV, dramatically
improving the visual prognosis.
Our prospective quasi- experimental study was carried out on 30 eyes of
patients with neovascular ARMD at the Ophthalmic Outpatient Clinic at Suez
Canal University Hospital, to monitor the response of CNV to Anti-VEGF to more
efficient follow up and better visual outcome in this patient’s category.
Including, age group: 5o years and above, of both sexes, with stablished
diagnosis of AMD neovascularization using fluorescein angiography and spectral
domain OCT, and only with clear identification of the morphology and extent of
neovascularization on OCTA were enrolled in this study.
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Excluding patients with history or clinical evidence of diabetic retinopathy,
any significant media opacity that could affect image quality, myopia greater than
6 diopters, glaucoma and other hereditary, inflammatory and/or vascular chorio