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Abstract The present study was cross sectional observational one which included 175 patients presented with ST elevation myocardial infarction undergoing primary PCI in Assuit University Hospital. Patients were classified into 2 groups: addict group which comprised 75 patients & non-addict group which comprised 100 patients Diagnosis of STEMI was according to ESC criteria (2018). Diagnosis of addict patients was according to WHO DSM-5 criteria for addiction (2018) in which the person must demonstrate 2 of the 11 criteria mentioned before within a 12-month-period in addition to the results of urinary screening testAll included patients were subjected to:A. Full historytaking B. Thorough General & Cardiac examination was done for all patients. C. Twelve lead EC D. Full labs E. Echocardiography. F. Coronary Angiography. F. PCI. G. In-hospital follow up after the procedure: Regarding chest pain & need to reintervention, hemodynamic stability, heart failure & score of Killip classification, Electrical instability (rhythm disorders) including tachy & bradyarrythmias whether supraventricular or ventricular arrhythmias, GIT bleeding & Acute kidney injury The major findings of the present study were that: The mean age for non-addict patients was significantly higher compared to addict ones. Out of the addict patients, 27 patients (36 %) were addict to cannabis, 24 patients (32 %) addict tramadol, 15 patients (20%) were addict to opium while 9 patients (12 %) were addict to poly substances. Diabetes and hypertension as co-morbid conditions were significantly higher among non addict group of patients in comparison to addict group. All addicts were smokers while non-smokers comprised 40% of non-addict patients which was highly significant. |