الفهرس 
epidemiologyOnly 14 pages are availabe for public view
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Abstract
Background: COVID-19 infection had a variety of neurological manifestations, either affecting central or peripheral nervous system, they may accompany infection or develop post infectious. Also the newly developed COVID-19 vaccines, were associated with several neurological complications. Aim of the work: determine the spectrum of neurological clinical presentations among patients admitted in Neurology Department of Fayoum University Hospitals before, during and after Covid-19 era. methods: it was historical cohort study, Data collected from records at Fayoum University Hospitals statistics department about patients who admitted at neurology department before, during and after COVID -19 infection waves. Based on COVID-19 suspicion, and vaccination imposed by the national authorities, the study population were sub divided into suspected, confirmed and non-COVID patient groups, and to vaccinated and non-vaccinated groups respectively and different neurological complications were compared among these groups. Results: there was a significant increase in neurological manifestations complicating COVID-19 infection especially autoimmune complications reaching up to 71%, there was a significant worse prognosis of cases by COVID19 infection (66%), as regards vaccination, there was significant increase in different forms of neurological complications except for vascular complications (41%), with no statistical difference between different vaccine types, while prognosis of vaccinated cases show better outcome (52%), this study show that d-dimer and lymphopenia are of a higher level among COVID cases. conclusion: COVID-19 infection significantly increase different neurological complications especially autoimmune ones, and affect prognosis markedly, in addition, COVID vaccines cause different forms of neurological complications except for vascular ones, but show better prognosis