الفهرس 
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Abstract
This study aimed to assess and compare the prognostic value of MEWS and REMS models with laboratory markers for in-hospital mortality of critically ill patients with COVID-19 presenting to the Emergency Department.
The cross sectional study was carried out at the emergency department at Suez Canal University hospital, Ismailia city, Egypt on 92 patients 18 years or older with confirmed COVID - 19 presenting at emergency department at Suez Canal university hospital.
In our study, prevalence of death was 31/92 patients (33.7%), with significantly longer onset of symptoms and higher percentage of patients with chronic liver disease than in non survivors than survivors, whilepercentage of patients with previous stroke was significantly higher in survivors than non survivors.
The current study results found statistical significant difference between both groups regarding SPO, MAP that was higher in survivors than non survivors, while RR and HR that were higher in non survivors than survivors.
This study results showed that there was significant difference between both groups regarding WBCs, neutrophil, serum creatinine at follow up, ALT, AST (at admission and at follow up) that were higher in non survivors than survivors and regarding monocyte at admission, lymphocyte at follow up and platelets at follow up that were lower in non survivors than survivors.
The current study revealed that inflammatory markers showed significant difference between both groups regarding D dimer, ferritin and IL-6 at admission and after follow up and regarding CRP, LDH and PCT after follow up that were higher in non survivors than survivors. Also, there
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was significant difference in each group regarding inflammatory markers and D dimer at admission and at follow up except LDH in survivors group and PCT in each group.
Our study results showed that there was significant difference between both groups regarding CORAD that was higher in non survivors than survivors and discharge date that was longer in survivors than non survivors.
In this study D-Dimer used in prediction of mortality with sensitivity (88%) and specificity (79%) at admission and sensitivity (96%) and specificity (86%) at follow up. CRP used in prediction of mortality with sensitivity (58%) and specificity (48%) at admission and sensitivity (96%) and specificity (59%) at follow up. Ferritin used in prediction of mortality with sensitivity (87%) and specificity (56%) at admission and sensitivity (88%) and specificity (64%) at follow up. LDH used in prediction of mortality with sensitivity (67%) and specificity (58%) at admission and sensitivity (96%) and specificity (60%) at follow up. PCT used in prediction of mortality with sensitivity (61%) and specificity (50%) at admission and sensitivity (80%) and specificity (56%) at follow up. IL-6 used in prediction of mortality with sensitivity (67%) and specificity (60%) at admission and sensitivity (96%) and specificity (87%) at follow up.
The present study found that there was significant difference between both groups regarding median of MEWS (4 vs. 3, p=0.004) and REMS (9 vs. 6, p<0.001) that were higher in non survivors than survivors.
In our study, REMS was better than MEWS score in prediction of mortality with