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Abstract Medicinal plants are thought to be a possible source of components with therapeutic activity, they play a significant role in the advancement of pharmaceutical technology. Consequently, the therapeutic potential of many medicinal plants is continuously investigated. Gardenia thunbergia Thunb., often known as the white Gardenia or Forest Gardenia, is a small tree or shrub that is evergreen with fragrant white blooms that can reach heights of up to five meters (1). The Eastern Cape and KwaZulu-Natal Provinces of South Africa, Southern Mozambique, and Eastern the African nation of Swaziland are all natural habitats for the species (2). According to the reported data, several Gardenia species contain compounds that are useful for treating a range of human ailments (3). These kinds of plants are an excellent supplier of flavonoids, steroids, and phenolic chemicals (4). African herbal medicine uses roots, leaves, bark, and latex of Gardenia thunbergia Thunb. The roots of Gardenia thunbergia Thunb. have been discovered to be used in skin conditions and leprosy-related infections of the skin (5). Despite the previously mentioned data, not enough research has been done concerning the phytochemistry and biological activities of Gardenia thunbergia Thunb. which is grown in Egypt (6). As a result, it is crucial to examine the plant phytochemically and biologically in order to identify potential new therapeutic targets for both the management and avoidance of various diseases. |