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العنوان
Efficacy of Native T1 Mapping in Comparison to Late Gadolinium Enhancement Technique for Assessment of Myocardial Viability in chronic Myocardial Infarction /
المؤلف
Diab, Mahmoud Salem Ahmed
هيئة الاعداد
باحث / محمود سالم أحمد دياب
مشرف / عزة عبد الحميد جاد
مشرف / ماري ربيع محروس
مشرف / أحمد رضا عبداللطيف
الموضوع
Diagnostic Radiology.
تاريخ النشر
2022
عدد الصفحات
144 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة قناة السويس - كلية الطب - Diagnostic Radiology
الفهرس
Only 14 pages are availabe for public view

from 160

from 160

Abstract

Myocardial infarction may lead to reversible (viable/stunned) and irreversible (non-viable) myocardial injury, even after successful coronary reperfusion. Early recognition of viable myocardium after a myocardial infarction (MI) is of clinical relevance as the affected segments have the potential for recovery. Determining the state of myocardial viability after ischemic insult is the base to make appropriate management plan. The gold standard modality for viability assessment is LGE-MRI. However, several emerging techniques are suggested to establish the diagnosis without need for the contrast media. T1 Mapping is a novel non-contrast CMR imaging tool that able to quantify the segmental biologically myocardial changes.
This study was conducted at MRI unit - Suez Canal university Hospital using 1.5T magnetic resonance system (Achieva dStream 1.5T, Phillips Medical Systems). 43 patients with chronic MI were included aiming to assess the diagnostic performance of native T1 value for detection of myocardial viability using LGE ≥ 75% transmurality as a reference standard to define ischemic non-viable myocardium.
The MRI protocol was consistent of black blood axial, coronal and sagittal plain images, steady-state free precession (SSFP) cine images of two-, three- and four-chamber long-axis views, short-axis volume data acquisition for evaluation of left ventricular (LV) and right ventricular (RV) function and dimensions. Phase-contrast velocity images at the level of aortic and pulmonary valves were obtained. For native T1 mapping, pre-contrast MOLLI 5(3)3 acquisition protocol was used. The LGE is obtained imaging 8-10 minutes after intravenous administration of contrast media. All image analyses were performed on cvi42 (Circle