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Abstract The different techniques of hepaticojejunostomy (HJ) are understudied. The aim of the study was to compare the surgical outcomes of conventional duct to mucosa hepaticojejunostomy and mucosal fixation hepaticojejunostomy. Hepaticojejunostomy is regarded as the definitive management of iatrogenic bile duct injuries, as well as the manner for restoring biliary enteric continuity after resection of benign or malignant tumours. Records of patients treated by HJ at the department of surgery, Medical research institute, Alexandria University and Gastroenterology surgery unit, Alexandria main university hospital were divided into two groups: those who underwent conventional duct to mucosa hepaticojejunostomy (G1) and mucosal fixation hepaticojejunostomy (G2) The primary outcome measure was the rate of bile leakage; secondary outcomes included; operative time, day to resume oral feeding, postoperative morbidity and mortality. One hundred and forty three patients treated by HJ were divided into 2 groups. The mean duration of the hepaticojejunosotmy anastomosis was 29.88 ± 6.72 in G2 vs 32.45 ± 7.43 in G1. The overall morbidity in the mucosal fixation HJ group was significantly lower than in the conventional HJ group (23/52 (44.2 %) vs 56/91, 61.5 %, P=0.045). Biliary leakage incidence was higher in group 1 (21, 23.1%) than in group 2 (5, 9.6%, (P=0.045) with re-exploration required in 2 patients. The duration of hospital stay and time to start oral feeding were longer in G1 compared to G2 |